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It was withdrawn during phase 3 due to heart failure problems, but is still in clinical development for alternative indications

Its important to adjust treatment for each patient to make it work best

Reduces inflammation

Ongoing clinical trials test the efficiency of immune system-activating monoclonal antibodies Ipilimumab and Pembrolizumab in melanoma treatment [2, 8, 9]

The epitope summary ( Figure 6A ) also reveals multiple predicted B-cell, CD4, and CD8 T-cell epitopes in Pf CSP, Pb SLTRiP, and Pf SLTRiP antigens, whereas CD8 and CD4 T-cell predictions identify regions with high predicted MHC I and II binding affinity that overlap with putative B-cell epitopes ( Supplementary Figure S6 )